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28th June 2001

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Increasing diagnosis and treatment rates

UI therapy market turns lucrative
Waltham, Mass.

Urinary incontinence (UI) is the subject of a new study from Decision Resources, Inc., that examines the significant market opportunities associated with this condition.

More than 145 million people experienced some form of involuntary urine loss in the seven major pharmaceutical markets (US, France, Germany, Italy, Spain, UK, and Japan) in 2000. Of this group, more than 72 million people can be classified as having significant UI. Of this potentially treatable population, only about 20 per cent of patients are diagnosed, and even fewer receive pharmacological therapies for their condition.

Thus, UI offers a ripe opportunity for current and emerging therapies. Two major players in the UI marketplace, Pharmacia and Alza, have initiated direct-to-consumer advertising campaigns to bolster their stakes in the growing market for UI products. These efforts will alert patients and physicians to the availability of improved therapies and increase the number of patients seeking medical treatment.

Tolterodine (Pharmacia’s Detrol), recently launched in all major markets except Japan (where it is in phase II development), and extended-release oxybutynin (Alza’s Ditropan XL) in the US and the UK, represent the first major pharmacological breakthroughs in UI in two decades and have enlivened commercial interest in the UI market-especially the market for overactive bladder therapies.

The increasing R&D efforts inspired by these agents should drive impressive growth for this indication within our 2000-2010 forecast period. The market for agents to treat UI totalled $722 million in 2000. During the study period, factors influencing pharmaceutical sales will include:

  • Increases in the percentage of patients who are diagnosed and drug- treated, better patient compliance
  • The emergence of a broader choice of drug therapies.

In particular, promising therapies could include Pfizer’s darifenacin, an M3-specific muscarinic antagonist in phase III development; resiniferatoxin (Afferon’s RTX) a neuronal desensitising agent; and (AstraZeneca’s ZD- 0947), a potassium-channel opener. The launch of these new drugs could significantly boost the market for UI therapies, allowing it to reach nearly $2 billion by 2010.

UI offers invaluable market intelligence for pharmaceutical companies developing drugs to treat this indication. This study is part of Mosaic, one of six Pharmacor services available from Decision Resources that evaluate the commercial potential of drugs in research and development. Decision Resources, Inc., is a world leader in research publications, advisory services, and consulting designed to help clients shape strategy, allocate resources, and master their chosen markets.

PRNewswire

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