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28th June 2001

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Glaxo earmarks Rs 18,000 cr for genomic research
Gireesh Chandra Prasad G I - New Delhi

Global pharma giant GlaxoSmithKline (GSK) has earmarked a whopping sum of Rs 18,000 crores for developing genomic drug targets in two major disease segments, viz., obesity and oncology.

The company has already identified genomic targets for obesity, colon cancer, ovarian cancer, breast cancer and lung cancer. This long-term project is expected to reach fruition by 2005 when the company expects to market the first genomic drug, a Glaxo India official told Express Pharma Pulse.

Another promising candidate for GSK is a product for septic shock. The compound GR 270773, which is soon to enter phase 2 trials, has been licensed from New York-based Sepsicure. The company aims to launch the product in the international markets by 2004.

Back home, in India, Glaxo India (yet to be merged with SmithKline Pharma) is planning to launch two combination vaccines in the near future. One of them is ‘Twin Rix’, a combination for hepatitis-A and B, which is expected by the end of 2001 or in the first quarter of 2002. The other vaccine is a combination of DPT vaccine and hepatitis-B vaccine, it is learn't.

Recently, Glaxo laun-ched its smoking cessation pill bupropion hydrochloride SR under the trade name Zyban.

Though the drug is launched in the country only as a prescription medication for smoking cessation, bupropion is also seen useful in smokers suffering from Chronic Obstructive Pulmonary Disorder (COPD). Since the drug is used in over eighty countries, the Company is planning to seek special permission from the DCGI to market the drug for Chronic Obstructive Pulmonary Disease as well. However, sources said that this may be attempted only after six months from now.

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