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28th June 2001

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Lexicon announces tech sublicensing programme for academic research

Lexicon Genetics Incorporated announced on behalf of Lexicon and Taconic Farms, Inc. a technology sublicensing programme that permits academic research use of positive-negative selection and isogenic DNA technologies for the generation and use of transgenic and knockout mammalian models of human gene function. This program makes these patented technologies available to academic institutions around the country, while protecting the commercial interests of Lexicon and Taconic.

‘‘Academic researchers at institutions that sign this agreement will benefit from no-cost access to the patent rights necessary to generate these models,’’ said Mark J Logan, Manager of Business Development at Lexicon. ‘‘We believe our academic sublicensing program benefits both industry and academia by providing a roadmap for eliminating the intellectual property uncertainties surrounding the commercially valuable discoveries made using these technologies.’’

‘‘The flexibility provided by this agreement assures that researchers have a number of collaborative options and resources to assist in the development and testing of their models,’’ said Donna Gulezian, Transgenic Division Product Manager at Taconic.

‘‘Furthermore, this sublicensing program promotes the sharing of research tools in the spirit of the recommendations of the National Institutes of Health.’’

Several leading academic institutions have already signed this license agreement, and Lexicon has received numerous additional unsolicited inquiries from academic institutions seeking similar agreements.

Researchers at academic institutions that obtain sublicenses may use the licensed technologies to generate transgenic and knockout mammalian models of human gene function. The resulting models may be used in-house for non- commercial research, and may be freely transferred to collaborators at other licensed academic institutions.

Academic researchers at participating institutions may use models made using the licensed technologies to engage in sponsored research or commercial collaboration arrangements with companies that are licensed by Lexicon. Researchers who wish to distribute or commercialise the models may do so under separate material transfer arrangements with Taconic. In addition to granting the research sublicense, the agreement with Lexicon and Taconic allows each research institution to receive knockout models from third parties, provided that all conditions stipulated within the licensing agreement are met.

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